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Using two separate drugs to lose weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the people who go through it you need to err to the side of caution and permit the FDA do its job and demand some study be done so your public understands the side effects and dangers of the medications before we drive them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on his or her medications.

Researchers found out that participants investing in this drug to get a year, dropped a few pounds within a month and have kept the load off during the entire 56 weeks of the study. Contrave is really a combination from the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs that are made up of several active ingredient, which may make them far better and safer.

Combo-pilling is the newest fad or better yet the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is now popular will be the fact that by right now there aren't any long term prescription slimming capsules that have been licensed by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be licensed by the FDA.

Seizures certainly are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug could also raise hypertension and pulse rate, and must not be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure levels and heartrate and must not be used in patients with uncontrolled high blood pressure levels, along with by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients for the increased likelihood of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.

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